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Physiology of Growth and Quality of Products

Some activities of the Growth team

Context and ambition

Pork is one of the most commonly consumed meats worldwide. Pork production has to conciliate economic outcome, social expectations, and quality of its products. Improving the efficiency of pork production notably requires specific knowledge on the developmental dynamics of tissues. The mechanisms controlling energy reserves in tissues together with the communication between organs ruling nutrient use are also of upmost importance to cope with rearing pressures.

Our ambition is to identify the mechanisms associated with the plasticity of production tissues from the foetal period to puberty, and to propose new tools to act on growth trajectories and meat quality traits. Predicting pork quality traits are based on molecular and cellular indicators (biomarkers) in muscle tissues.

Objectives

  • Determining the developmental and regulatory mechanisms allowing cell development and tissue growth (muscle, fat and liver) in response to disturbances of the foetal environment
  • Understanding the responses of lean and fat tissues to rearing constraints considering metabolic flexibility as a target for successful life-time interventions
  • Unravelling by mathematical models the hierarchy of actors involved in tissue responses and predicting the quality of pig carcasses and pork

Expertise and skills

The complementary expertise of our team members involves scientific knowledge on the lineages of multi-potent cells, the dynamics in expression levels of various genes and proteins in muscle and adipose tissues, and the roles of key actors in the flexibility of energy reserves and cell structures. Exchanges (circulating nutrients, gas, and hormones) between cells, tissues and organs are also considered.

Methodological skills
  • Cell culture
  • Molecular biology, including transcriptomics
  • Protein separation, including proteomics
  • Metabolite and hormone quantifications
  • Physical-chemistry of food products
  • Bioinformatics and mathematical models

People

Members of the Growth team
Responsable équipe Croissance
Isabelle Louveau

Leader of the "Physiology of Growth and Quality of Products" team

Phone: (+33) 2 23 48 50 46
Mail: Isabelle Louveau

Scientists
Frédéric Dessauge
Mohammed Gagaoua
Florence Gondret (cv Hal)
Bénédicte Lebret
Isabelle Louveau
François Moreews
Marie-Hélène Perruchot

Technicians

Nathalie Bonhomme
Sophie Daré
Frédérique Mayeur
Annie Vincent
Sandrine Tacher
Christine Tréfeu

PhD students
Camille Juigne
Chloé van Baelen

Formers members :
Rosa Castellano Perez (post-doc)
Patrick Ecolan
Maëva Jegou (PhD defended in 2016)
Basile Koffi (post-doc)
Louis Lefaucheur
Farouk Messad (post-doc)
Hieu Nguyen Ba (subject of thesis ; PhD defended in 2020)
Clémence Panzuti (subject of thesis ; PhD defended in 2018)
Audrey Quéméner (PhD defended in 2021)
Kamil Sierzant (post-doc)
Masoomeh Taghipoor