Know more

Our use of cookies

Cookies are a set of data stored on a user’s device when the user browses a web site. The data is in a file containing an ID number, the name of the server which deposited it and, in some cases, an expiry date. We use cookies to record information about your visit, language of preference, and other parameters on the site in order to optimise your next visit and make the site even more useful to you.

To improve your experience, we use cookies to store certain browsing information and provide secure navigation, and to collect statistics with a view to improve the site’s features. For a complete list of the cookies we use, download “Ghostery”, a free plug-in for browsers which can detect, and, in some cases, block cookies.

Ghostery is available here for free:

You can also visit the CNIL web site for instructions on how to configure your browser to manage cookie storage on your device.

In the case of third-party advertising cookies, you can also visit the following site:, offered by digital advertising professionals within the European Digital Advertising Alliance (EDAA). From the site, you can deny or accept the cookies used by advertising professionals who are members.

It is also possible to block certain third-party cookies directly via publishers:

Cookie type

Means of blocking

Analytical and performance cookies

Google Analytics

Targeted advertising cookies


The following types of cookies may be used on our websites:

Mandatory cookies

Functional cookies

Social media and advertising cookies

These cookies are needed to ensure the proper functioning of the site and cannot be disabled. They help ensure a secure connection and the basic availability of our website.

These cookies allow us to analyse site use in order to measure and optimise performance. They allow us to store your sign-in information and display the different components of our website in a more coherent way.

These cookies are used by advertising agencies such as Google and by social media sites such as LinkedIn and Facebook. Among other things, they allow pages to be shared on social media, the posting of comments, and the publication (on our site or elsewhere) of ads that reflect your centres of interest.

Our EZPublish content management system (CMS) uses CAS and PHP session cookies and the New Relic cookie for monitoring purposes (IP, response times).

These cookies are deleted at the end of the browsing session (when you log off or close your browser window)

Our EZPublish content management system (CMS) uses the XiTi cookie to measure traffic. Our service provider is AT Internet. This company stores data (IPs, date and time of access, length of the visit and pages viewed) for six months.

Our EZPublish content management system (CMS) does not use this type of cookie.

For more information about the cookies we use, contact INRA’s Data Protection Officer by email at or by post at:

24, chemin de Borde Rouge –Auzeville – CS52627
31326 Castanet Tolosan CEDEX - France

Dernière mise à jour : Mai 2018

Menu Logo Principal Agrocampus Ouest Rennes 1 University Logo Igepp

Home page

Rafaëla Lopez-Martin

Study of action mode of defense elicitors in the pathosystem Potato / Phytophthora infestans

Thesis started December 1st 2016, defended in july, 13th
Encadrant : Florence Val



The induction of response defences via the Pathogen-Associated Molecular Pattern (PAMP)-Triggered Immunity provides all plants an arsenal of antimicrobial compounds against pathogens. Stimulation of these defences by exogenous elicitors could be a strategy to reduce the pesticides but this requires a better understanding of the induction mechanisms. This induction could depend on both the origin of the elicitor and the genotype. Two potato genotypes partially resistant to Phytophthora infestans were treated with a PAMPs from P. infestans, the Concentrated Culture Filtrate (CCF), a synthetic molecule, the β-aminobutyric acid (BABA); and an Ulva spp extract. 48h after treatment, the induced metabolites in the leaflets were first compared by a non target metabolomic using a UPLC-qTOF-MSe, then through targeted metabolomic and transcriptomic approaches. The results showed that (i) each elicitor induced a specific metabolic profile reprogramming: the BABA and the CCF induced the benzylisoquinoline alkaloids and the Ulva extract, the alkaloid sterols and phenylpropanoids; (ii) the transcript analysis partially confirmed these inductions; (iii) the signalling depended on the JA pathway for the Ulva extract while it is rather SA pathway-dependent for the BABA and CCF; (iv) the abundance of several antimicrobial metabolites was genotype-dependent. Our results suggest that the induction of the antimicrobial compounds depends on the elicitor/genotype interaction and on the specific perception of the elicitor. In order to improve their efficiency in the field, special attention should be paid on the defence-related metabolic print generated by each elicitor.

Poster au format pdf